[Non-fatal paliperidone overdose: a case report].

نویسندگان

  • Jesjeet Singh Gill
  • Subash Kumar Pillai
  • Ong Hui Koh
  • Stephen Jambunathan
چکیده

Paliperidone, a novel serotonin and dopamine antagonist, is one of the newest atypical antipsychotics on the market. It is an orally administered drug that is indicated for the treatment of schizophrenia, and is considered to be safe and well tolerated. A 37-year-old female with a long-standing history of schizophrenia had been taking paliperidone 12 mg d-1 for about 1.5 years. She overdosed on a total of 756 mg of paliperidone in response to auditory command hallucinations. She was promptly hospitalized, and fortunately did not suffer any major adverse clinical events, adverse laboratory parameters, or long lasting sequelae. Herein we discuss the inherent characteristics of paliperidone that limit the danger associated with overdosing.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Successful Management of Vinblastin Overdose with Exchange Transfusion: A Case Report

Accidental overdose of chemotherapy drugs including vinblastin (VBL) have been reported in the literature. As VBL overdose is potentially fatal, we decided to introduce a 2-year-old girl affected by langerhans’ cell histiocytosis who was accidentally injected 10-times the prescribed dose of VBL (16 mg), and was saved with whole blood double exchange transfusion at 8 and 20 hrs after the acciden...

متن کامل

تجربه بیش‌مصرف غیرکشنده مواد در دوران زندگی در سوءمصرف‌کنندگان مواد در ایران

Objectives: The present study was carried out with the purpose of investigating lifetime non-fatal overdose of illicit addictive substances, its relationship with demographic characteristics, and pattern of abuse in individuals with substance dependency. Method: In a descriptive study, data were gathered from 29 provinces in Iran from May to September 2008. Addicted individuals were interviewed...

متن کامل

Hypoxic-ischemic encephalopathy in a young man due to tramadol overdose

Objective: Tramadol is a synthetic analgesic with two mechanisms. The opioid and non-opioid mechanisms are responsible for tramadol side effects. Non-opioid side effects of tramadol are due to the reuptake inhibitions of serotonin and norepinephrine. Some of the side effects include anaphylactoid reactions, CNS depression, hypoglycemia, hypotension, respiratory depression, seizures, and seroton...

متن کامل

Predictors of non-fatal overdose among a cohort of polysubstance-using injection drug users.

BACKGROUND Non-fatal overdose is a major determinant of morbidity among injection drug users (IDU). We sought to evaluate factors associated with non-fatal overdose among IDU in Vancouver. METHODS We examined non-fatal overdose among participants in the Vancouver Injection Drug Users Study. Correlates of non-fatal overdose occurring between 1996 and 2004 were identified using generalized esti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Turk psikiyatri dergisi = Turkish journal of psychiatry

دوره 21 4  شماره 

صفحات  -

تاریخ انتشار 2010